In your first post, you were talking about select some text and then space bar to erase it. That was definitely a problem in 14.0.
In your 2nd post, you said Select text, then CTRL+Enter. That should run the selected text as SQL.
I haven't heard of any problems with that.
Does it happen no matter what you select? Can you just start Toad, type in something simple like "select * from dual", select it, then CTRL+Enter and Toad freezes?
Can you send me your user files folder so that I can try it with your settings? You can find steps on how to do that, as well as my email address here.
Thanks