The tool-tip on the Cache box says “Leave blank for no cache”
However, if you leave it blank, the generate SQL is incorrect:
ALTER SEQUENCE CHX_COMMON.MB_TOPIC_CONFIGURATION_ID
INCREMENT BY N
MINVALUE 1
MAXVALUE 9999999999999999999999999999
CACHE 1
NOCYCLE
NOORDER;
If you enter 0, the generated SQL is correct and specifies NOCACHE.
Found this in 12 GA, but also a problem in 12.1.0.2