Cannot connect to local storage after update

Using TOAD Data Point Pro and I am getting the following error when trying to connect to local storage after upgrade from 4.3 (64 bit) to (64 bit).

Any ideas on how to fix?

There was a connect error. Check that the server, username, password and port are correct, that you have registered this user using the registration tab, and that the registered user has not been disabled: The requested address is not valid in its context

Does it occur every time? Can we get a screenshot? When does it happen?