Toad compare 2018

please how compare between running database with Dump file by using toad for oracle

Toad cannot compare a live database to a datapump file, sorry.

Thanks for your reply
Can we import or export from dump file

Yes. From the main menu:

Database -> Export -> Data Pump Export


Database -> Import -> Data Pump Import

Those require either the DB Admin module or the Professional Edition in your Toad license.