Toad ( Ctrl+Enter is not working in new version of Toad

In previous version of Oracle I used to execute statements using Ctrl+Enter Now is not working anymore.

Is there a new setting I need to check in this new version of toad?

Edit: I just tried again using Ctrl+Enter and now it works as expected. It seems to be an intermittent issue.

If issue is intermittent,
Is it possible that there's a conflict with the Ctl-Enter shortcut?
that you've assigned Ctl-Enter to another capability within Toad,
that another application (or Windows?) has Ctl-Enter assigned ?